Protein Info for PS417_16925 in Pseudomonas simiae WCS417

Annotation: MarR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 157 PF22381: Staph_reg_Sar_Rot" amino acids 28 to 109 (82 residues), 39.7 bits, see alignment E=8.6e-14 PF12802: MarR_2" amino acids 36 to 95 (60 residues), 51.8 bits, see alignment E=1.5e-17 PF01047: MarR" amino acids 39 to 96 (58 residues), 60.1 bits, see alignment E=3.2e-20 PF13463: HTH_27" amino acids 39 to 104 (66 residues), 36.2 bits, see alignment E=1.2e-12

Best Hits

Swiss-Prot: 40% identical to MARR_ECOLI: Multiple antibiotic resistance protein MarR (marR) from Escherichia coli (strain K12)

KEGG orthology group: K03712, MarR family transcriptional regulator (inferred from 84% identity to pfs:PFLU3878)

Predicted SEED Role

"Transcriptional regulator, MarR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See U1SZY8 at UniProt or InterPro

Protein Sequence (157 amino acids)

>PS417_16925 MarR family transcriptional regulator (Pseudomonas simiae WCS417)
MPHFTPDSFRNCHLGLLLGRAALLKDRIIDTHMEPHGVTAAQFKVLIIIAQFDVDTPAEL
CRNLSLDSGSMTRMLDRLEQKGLLARQRSEQDRRQVRLVLTEDGKRLADMLPYIGAQSMN
ELAGALEPGELQTLERILKKILVAAGDAIVIQRVGNQ