Protein Info for GFF3304 in Variovorax sp. SCN45

Annotation: Monofunctional biosynthetic peptidoglycan transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 transmembrane" amino acids 7 to 31 (25 residues), see Phobius details PF00912: Transgly" amino acids 240 to 391 (152 residues), 153.2 bits, see alignment E=2.5e-49

Best Hits

KEGG orthology group: None (inferred from 84% identity to vpe:Varpa_0020)

Predicted SEED Role

"Monofunctional biosynthetic peptidoglycan transglycosylase (EC 2.4.2.-)" in subsystem Peptidoglycan Biosynthesis (EC 2.4.2.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.2.-

Use Curated BLAST to search for 2.4.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (422 amino acids)

>GFF3304 Monofunctional biosynthetic peptidoglycan transglycosylase (Variovorax sp. SCN45)
VKKTLRIVLFSLMALVITACIAIFLIVKLALAPAAGEWSTTVKAGPLNFEIGVPTALRVA
TSPWFAPYLDGRSFDTRAGAVRFAWKPTGELLEMQCAPCSAEVPALGTQPIKVERLVATV
KRDGNTLNGTFEATPESTDTTRLHGHWEGKLTPKSLQLSANVEDAPIARWYAVLVPTLPE
LRSARIGGTLALHGQLLLPDATFSVQPTISQFTVEGLGTEAMLNARTSCGPSARLTNDSW
LARAVVAAEDQRFFTHAGYDLTEILASIDNNQKPGQTKRGGSTLTQQLAKLLVTGSDRTA
ERKLREMLYAVEMEQTLGKARILQLYLDNAPWGGSICGAEAAARRYFKRSARTLEPAQAV
WLAAMLHKPQAVLEQWRRDGHIDADRTKWVAESIRGINRNQREALLKSVAAAKFTAPEAV
TQ