Protein Info for PS417_16855 in Pseudomonas simiae WCS417

Annotation: cation:proton antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 112 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 41 to 62 (22 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details TIGR01300: monovalent cation/proton antiporter, MnhG/PhaG subunit" amino acids 12 to 98 (87 residues), 67.6 bits, see alignment E=4.7e-23 PF03334: PhaG_MnhG_YufB" amino acids 13 to 92 (80 residues), 72.3 bits, see alignment E=1.6e-24

Best Hits

Swiss-Prot: 40% identical to PHAG_RHIME: Probable K(+)/H(+) antiporter subunit G (phaG) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K05564, multicomponent K+:H+ antiporter subunit G (inferred from 99% identity to pfs:PFLU3868A)

Predicted SEED Role

"Na(+) H(+) antiporter subunit G" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UBF2 at UniProt or InterPro

Protein Sequence (112 amino acids)

>PS417_16855 cation:proton antiporter (Pseudomonas simiae WCS417)
MMPLWVEVIVAVLLVLSSVFALIGAIGLLRMKDFFQRMHPPALASTLGAWCVALASIIYF
SVLKSGPVLHGWLIPILLSITVPVTTLLLARTGLFRKRMAGDDVPAEVSSRR