Protein Info for PS417_16840 in Pseudomonas simiae WCS417

Annotation: monovalent cation/H+ antiporter subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 37 to 55 (19 residues), see Phobius details amino acids 75 to 103 (29 residues), see Phobius details amino acids 114 to 131 (18 residues), see Phobius details amino acids 134 to 153 (20 residues), see Phobius details amino acids 165 to 189 (25 residues), see Phobius details amino acids 210 to 236 (27 residues), see Phobius details amino acids 243 to 270 (28 residues), see Phobius details amino acids 284 to 303 (20 residues), see Phobius details amino acids 310 to 329 (20 residues), see Phobius details amino acids 335 to 354 (20 residues), see Phobius details amino acids 402 to 423 (22 residues), see Phobius details amino acids 429 to 449 (21 residues), see Phobius details amino acids 456 to 479 (24 residues), see Phobius details amino acids 496 to 516 (21 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 133 to 441 (309 residues), 95.4 bits, see alignment E=2e-31

Best Hits

KEGG orthology group: K05561, multicomponent K+:H+ antiporter subunit D (inferred from 98% identity to pfs:PFLU3866)

Predicted SEED Role

"Na(+) H(+) antiporter subunit D" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UDP5 at UniProt or InterPro

Protein Sequence (560 amino acids)

>PS417_16840 monovalent cation/H+ antiporter subunit D (Pseudomonas simiae WCS417)
MNWVNQLIVAPILLPLLTAALMLMLGEKRRPLKAKINLFSSVIGLGIAILLLYWTQKGGP
GSIGVYLPGNWQVPFGIVLVVDQLSALMLVLTGIIGVSALLFAMARWDRAGTSFHALFQI
QMMGLYGAFLTADLFNLFVFFEVLLAASYGLMLHGSGRARVSSGLHYIAINLLASSLFLI
GAAMIYGVTGTLNFADLALKIPLVPEADRGLLHAGAAILATAFLAKAGMWPLNFWLAPAY
SSASAPVAAMFAIMTKVGVYTVLRLWTLLFSGQAGASALFGGDWLVYGGMATILCAGLAM
VAAQRLERMASLSILVSAGILLSAVGFAQPSLTAGALFYLVSSTLALSALFLLAELIERS
RSANDLPLDEEIDALPKAMESLHPRPGVNLDDEQKAVVGQVIPWTMAFLGLSFVACALLI
IGMPPLSGFIGKLSLLSALVNPLGLGVSIDAPIRPAAWGLVALLILSGLASLIAFARLGI
QRFWTPEERPSPLLRRYECLPIFFLLGLSILLTFKAEPLMRYTQDTAVSLNNPEHYVMAV
MATRPVPSPEAKTAALEVQP