Protein Info for GFF3289 in Variovorax sp. SCN45

Annotation: Putative phosphoesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 39 to 59 (21 residues), see Phobius details amino acids 71 to 92 (22 residues), see Phobius details amino acids 119 to 138 (20 residues), see Phobius details PF00149: Metallophos" amino acids 163 to 343 (181 residues), 47.5 bits, see alignment E=1.5e-16

Best Hits

KEGG orthology group: K07098, (no description) (inferred from 91% identity to vpe:Varpa_0008)

Predicted SEED Role

"putative phosphoesterase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>GFF3289 Putative phosphoesterase (Variovorax sp. SCN45)
MPDPIAPMPIRPLSALTALLHAYIALRLLPALAVLTPAWPLALLALMVSALTIPLPFLSR
RIERNASMGEALKWIGLISMGWFSSMFVLTLVRDAGLLLTWLASALGGVQVQWNTLRPWS
ALAVLVIATATSAIGFLNARRTASVKRVEVPIRGLPQALEGFTIAQLSDIHVGPTIKSGY
IQRIVEVVNRLGADTIAITGDLVDGSVPELREHIAPLAGLRARHGTFVVTGNHEYYAGAH
AWIDELRRLGLKVLLNEHVVLQTRNVRGAQTDEELFESALVLAGVTDFTAGHFDAAHASD
PHLALHDAPPLVHTRVLLAHQPRSAPLAAAAGYQLQLSGHTHGGQFFPWNLFVPMQQPFT
AGLHRLHDMWVYVSRGTGYWGPPKRFGAPSEITLLTLVPAA