Protein Info for PS417_16735 in Pseudomonas simiae WCS417

Annotation: aldehyde dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00171: Aldedh
  • amino acids 62 to 502 (441 residues), 324.6 bits, E=4.6e-101

Best Hits

KEGG orthology group: K00131, glyceraldehyde-3-phosphate dehydrogenase (NADP) [EC: 1.2.1.9] (inferred from 95% identity to pfs:PFLU3844)

Predicted SEED Role

"Glyceraldehyde-3-phosphate dehydrogenase, putative"

MetaCyc Pathways

• superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle (18/22 steps found)
• glycolysis IV (8/10 steps found)

KEGG Metabolic Maps

• Glycolysis / Gluconeogenesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.1.9

Sequence Analysis Tools

See A0A1N7TYP1 at UniProt or InterPro

Protein Sequence (538 amino acids)

>PS417_16735 aldehyde dehydrogenase (Pseudomonas simiae WCS417)
MTTSNLLAQLFPDSAAEIPEQFQLGAPIEQRDYLVDGQLRVWSGPLAKVQSPVQFGDERV
HIGSTPLLDADTALTALDAAVRAYDRGQGEWPTMRVAERIQHVEAFLCRMREQRDAVVKL
LMWEIGKNLKDSQKEFDRTCDYITDTINALKELDRRSSRFELEQDTLGQIRRVPLGVALC
MGPYNYPLNETFTTLIPALIMGNTVVFKPAKLGVLLIRPLLEAFRDSFPAGVINVIYGSG
RETVSALMASGKIDIFAFIGTNKAASDLKKLHPKPHRLRAALGLDAKNPGIVLPDVDLDN
AVSEAVTGSLSFNGQRCTALKILFVHEDVVDRFIEKFNKKLATLKPGMPWEDGVALTPLP
EVGKVDYLNGLVADAAQQGATVVNEHGGESRGSFFYPAVLYPVNPQMRVYHEEQFGPVVP
IVPYRDLETVIDYVLDSDFGQQLSIFGTNAAEVGRLVDTFANQVGRININAQCQRGPDTF
PFNGRKNSAEGTLSVHDALRVFSIRTLVATKFQESNKALVSDILRNRDSSFLTTDYIF