Protein Info for GFF3263 in Sphingobium sp. HT1-2

Annotation: Ferrous iron transporter FeoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details transmembrane" amino acids 107 to 125 (19 residues), see Phobius details amino acids 217 to 243 (27 residues), see Phobius details amino acids 273 to 302 (30 residues), see Phobius details amino acids 307 to 323 (17 residues), see Phobius details amino acids 328 to 347 (20 residues), see Phobius details amino acids 358 to 383 (26 residues), see Phobius details amino acids 394 to 416 (23 residues), see Phobius details amino acids 455 to 476 (22 residues), see Phobius details amino acids 555 to 579 (25 residues), see Phobius details amino acids 591 to 612 (22 residues), see Phobius details PF01926: MMR_HSR1" amino acids 7 to 123 (117 residues), 72.3 bits, see alignment E=7.1e-24 PF02421: FeoB_N" amino acids 7 to 165 (159 residues), 183.5 bits, see alignment E=4e-58 PF07670: Gate" amino acids 285 to 380 (96 residues), 78.3 bits, see alignment E=1.1e-25 amino acids 455 to 585 (131 residues), 46 bits, see alignment E=1.3e-15 PF07664: FeoB_C" amino acids 398 to 450 (53 residues), 59.8 bits, see alignment 3.3e-20

Best Hits

KEGG orthology group: K04759, ferrous iron transport protein B (inferred from 87% identity to sch:Sphch_2300)

Predicted SEED Role

"Ferrous iron transport protein B" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (618 amino acids)

>GFF3263 Ferrous iron transporter FeoB (Sphingobium sp. HT1-2)
MSGLPLVALVGNPNAGKSALFNALTGARQKLGNYPGVTVERKAGRLSLADGRPVELVDLP
GTYSLSPASPDEQVTRDFVLGKQAGEKLPDALVIVVDASNLDNHLRFALELIALGLPTVV
ALNMVDLATRDGLELDANVLARELGVPVVSTVAVRKRGLDHLKTELETLLGAQTGMLRAS
AGEPDFDAVRREARRIARAAIVRETPSRRLTAAVDRVALHPVLGLALLLGLLFVMFQAVF
SWASVPADMLEGWVTALGEAVTNTLPPGIIHDFLLQGVVGGVGAVIVFLPQILILFFFIL
MLEATGYMARAAFLMDGIMAKVGLSGRAFIPLLSSFACAVPGIMATRTISDPKDRLTTIL
IAPLMTCSARLPVYGLIIAAFIPARSVGPGIGLQGLVLFLLYVAGIVGAMLAAWALRLTV
AKGRSGGFLMEMPKYQWPRPQDILIGLWQRGVIFLKRAGTIILATNIVLWVLASFPHAPE
GVKQSEYSIAGRIAGGINVLVEPIGFNRDISLALLPSMAAREVAVSAIATVYAIDAEDDA
EALEQGLGDRLAGRWSLATALAFLAWFVFAPQCISTIAVTRRETNGWKWPLFMIGYLFVL
AYAAAGVTYWAAVAMGLG