Protein Info for GFF3235 in Sphingobium sp. HT1-2

Annotation: Ferrichrome-iron receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 704 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07715: Plug" amino acids 60 to 153 (94 residues), 70.6 bits, see alignment E=1.5e-23 TIGR01783: TonB-dependent siderophore receptor" amino acids 62 to 704 (643 residues), 284 bits, see alignment E=1.4e-88 PF00593: TonB_dep_Rec_b-barrel" amino acids 241 to 660 (420 residues), 170.4 bits, see alignment E=1.3e-53

Best Hits

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (704 amino acids)

>GFF3235 Ferrichrome-iron receptor (Sphingobium sp. HT1-2)
LPSLRLARLCALPFLFAPLPVLAQAPLDAAAGDSDILVTARAQKLYRVEDSEIGKIPADP
MDIPQSVQVITSELIRDQGARDITDLYRNVAGVSANQYATVTYRGFRQESMFYDGLRGDP
FQGFAVPNLFSIDRVEFLKGPVGMLYGASSPGGMINYVTKKPQDKFAASVRAVVGNYDRY
GASGEVTGPIDANGVVAGRAGLFYESFDTVQRFSGSRSLVADGGLKFNLAPDTSLTVQAT
RYDQDLPGNRLRGVAIDADGNFLADRSWTHNEKNDRLDLKGTVLQARLDSRLSDAVSINA
SGRWFRYTEYQRYHEPLGPIDTDGDGVVDTQPREFRSQHRTIEGASLASNMIARLETGGI
KHTILVGADWYRETQDFSGVTIKGVPGLSLNNPVYGLSNPTEADLAGLTPEVNASRAHRY
GVYAQEQADIGEHVILVGGVRHDWFDDKDEIGGAYADGGRWSWRVGGIYKPVQSVSLYSS
YAQSFEPQSPGNQNPAVGGPFAPIASRQFEVGAKGELMQGKLQPTIALYHIVRNGIVQVD
PDLAPVNGLDQLSPVGEVTSKGIELTLAADISKNWVLTANYAYNDARITDSADGATIDNA
VGGRFPNAPHHQAGLWSRYQIPAWGTALALGGQYVSGQIDRRGAHISGFTVFDGSITQDL
GFAEAMIRVENIFDKTYAVATFDARKGAFVGRPRTVFLELRRDF