Protein Info for GFF3227 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 PF13175: AAA_15" amino acids 289 to 428 (140 residues), 51.7 bits, see alignment E=1.7e-17 PF13304: AAA_21" amino acids 314 to 428 (115 residues), 50.9 bits, see alignment E=3.8e-17

Best Hits

KEGG orthology group: None (inferred from 58% identity to apt:APA01_08350)

Predicted SEED Role

"ATPase component BioM of energizing module of biotin ECF transporter" in subsystem Biotin biosynthesis or ECF class transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (444 amino acids)

>GFF3227 hypothetical protein (Sphingobium sp. HT1-2)
VLRLHKFVVKGLFGEFDHEIPFKDEERITALIGPNGLGKTACLKLINALFRKQWSVFGST
EFHEIEYVFNDGSSVWVTHQLGVENETEVSDAIGVRFVTFDSAGAELDSWSPRSADESLG
KITRIENYLPFLTRTSPRSWSHDLTGQVFSLQEIYEYYNDQLPDHITRSLHSTPPASLAH
LIGQVDCHLIETQRLVVFHPDDVRRTSTASSSLAISRKAQTLKTIIAKELAKYAATSQSL
DRSFPRRVLQLGKISPLADISTRLSDLEDTRRELTEAGILDQEADAALPPITEIDSAIAA
VMNVYLDDTKKKLDVLERLQSRILLFIELIDNRFDPKFVKVDKSVGFIVRRSSEVIVPLD
KLSSGEQHQLVLFFELLFELKENALILIDEPELSLHISWQKKFISDLERIISLNNFDVLL
ATHSPQLVGEWEHLVVELGDVDPA