Protein Info for GFF3209 in Xanthobacter sp. DMC5

Annotation: Sensor protein QseC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 150 to 173 (24 residues), see Phobius details PF00512: HisKA" amino acids 229 to 290 (62 residues), 39.9 bits, see alignment E=3.5e-14 PF02518: HATPase_c" amino acids 338 to 434 (97 residues), 47.3 bits, see alignment E=2.5e-16

Best Hits

KEGG orthology group: K02484, two-component system, OmpR family, sensor kinase [EC: 2.7.13.3] (inferred from 88% identity to xau:Xaut_4962)

Predicted SEED Role

"Sensor histidine kinase"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>GFF3209 Sensor protein QseC (Xanthobacter sp. DMC5)
MSGRWSLRRRLGLWLALSVAALWLAAATVAGLVLQHEIDEVFDSALQEVAQRVLPLAYSE
LLAREDGAGAHHMPPVGPHREFITYVVRDAQGRVLLQSSDAEQMAIPTGLAPGFQTTPRL
RTYTEAAVRGTVIVTTAEELDHRAAAVWRAVMALIWPLVALVPIALAGVWLTLRLTLKPV
LAFRHAIAARGRGNLAPVPEQGLPEEMAPVAGAVNALMERLRGALEAERGFAANSAHELR
TPIAAALAQTQRLVAELPEGAAQERARTIAGALRRLSRLSEKLLQLAKAEGAGLLAEAPA
PLAPVLRHVIADLDRQTGRAEDIDLSIAAEGGPVSDLDPDAFAVLARNLIENALKHGAPD
TPVQVRLTADRLDISNHGPVVPAERMAQLLRPFERGPTGAEGSGLGLAIAAAICRGAGLS
LEIASPIPGETEGFSAIVRFTEPEKLTAS