Protein Info for GFF3191 in Xanthobacter sp. DMC5

Annotation: Sialic acid transporter NanT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 transmembrane" amino acids 37 to 56 (20 residues), see Phobius details amino acids 62 to 82 (21 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 160 to 182 (23 residues), see Phobius details amino acids 194 to 217 (24 residues), see Phobius details amino acids 249 to 268 (20 residues), see Phobius details amino acids 288 to 308 (21 residues), see Phobius details amino acids 317 to 336 (20 residues), see Phobius details amino acids 455 to 480 (26 residues), see Phobius details amino acids 499 to 518 (20 residues), see Phobius details amino acids 525 to 543 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 24 to 353 (330 residues), 105.2 bits, see alignment E=4.1e-34 amino acids 457 to 553 (97 residues), 27.6 bits, see alignment E=1.4e-10 PF07690: MFS_1" amino acids 28 to 336 (309 residues), 85.9 bits, see alignment E=2.7e-28

Best Hits

KEGG orthology group: None (inferred from 91% identity to xau:Xaut_3353)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (555 amino acids)

>GFF3191 Sialic acid transporter NanT (Xanthobacter sp. DMC5)
MSVTTAGAAAKPRPMSREEKKVIFASSLGTVFEWYDFYLYGSLAAIIGAQFFSAYPPATR
DIFALLAFAAGFLVRPFGAIVFGRIGDLVGRKYTFLVTILIMGLSTFIVGILPNAASIGI
AAPIILIGLRLLQGLALGGEYGGAATYVAEHAPHGRRGFYTSWIQTTATLGLFLSLIVIL
FTRTIVGEQNFAAWGWRVPFLVSIALLGISVWIRLQLSESPTFQKMKEEGTTSKAPLSEA
FAKWGNLKVVLIALFGLVAGQGVVWYTGQFYALFFLQSILKVDGYTSNLLIAWSLVFGTG
FFVFFGWLSDKIGRKPIILAGCLIAAASYFPLFNMITTYANPALEKAIQNIRVTVVSDPA
NCGSLFNPVGTRIYTQPCDLARDFLAKSSVKYSTEAGPAGSPVQLKINDTVIPYTPDFNK
NALAALQTAGYPAAATNKDVVKMAHPFDIFRPQVAAVIGLLFILVLFVTMVYGPIAAALV
ELFPARIRYTSMSLPYHIGNGWFGGLLPATAFAMVAATGDIYYGLWYPIVIALMTFVIGL
LFVPETKDRNIDHWH