Protein Info for GFF3184 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Putrescine aminotransferase (EC 2.6.1.82)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03372: putrescine aminotransferase
  • amino acids 8 to 449 (442 residues), 939 bits, E=1.9e-287
• PF00202: Aminotran_3
  • amino acids 74 to 448 (375 residues), 338.1 bits, E=3.1e-105

Best Hits

Swiss-Prot: 100% identical to PAT_SALTY: Putrescine aminotransferase (patA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K09251, putrescine aminotransferase [EC: 2.6.1.82] (inferred from 99% identity to spq:SPAB_04016)

MetaCyc: 94% identical to putrescine aminotransferase (Escherichia coli K-12 substr. MG1655)
Putrescine aminotransferase. [EC: 2.6.1.82]; 2.6.1.82 [EC: 2.6.1.82]; Diamine transaminase. [EC: 2.6.1.82, 2.6.1.29]

Predicted SEED Role

"Putrescine aminotransferase (EC 2.6.1.82)" in subsystem Arginine and Ornithine Degradation (EC 2.6.1.82)

MetaCyc Pathways

• L-lysine degradation I (7/7 steps found)
• L-lysine degradation X (5/6 steps found)
• putrescine degradation I (2/2 steps found)
• superpathway of L-arginine and L-ornithine degradation (9/13 steps found)
• superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (7/11 steps found)
• superpathway of ornithine degradation (4/8 steps found)
• superpathway of L-lysine degradation (14/43 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.29 or 2.6.1.82

Protein Sequence (459 amino acids)

>GFF3184 Putrescine aminotransferase (EC 2.6.1.82) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
LNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAG
GDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQE
LLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAF
HGKSLGALSATAKSTFRRPFMPLLPGFRHVPFGNIDAMSMAFSEGKKTGDEIAAVILEPI
QGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAK
ALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAE
QKGDTLLDGFRQLAREYPNLVHDARGKGMLMAIEFVDNETGYRFASEMFRQRVLVAGTLN
NAKTIRIEPPLTLTIELCEQVLKSARNALAAMQVSVEEV