Protein Info for GFF318 in Sphingobium sp. HT1-2

Annotation: Signal recognition particle receptor FtsY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 PF02881: SRP54_N" amino acids 23 to 87 (65 residues), 42.3 bits, see alignment E=1.4e-14 TIGR00064: signal recognition particle-docking protein FtsY" amino acids 37 to 305 (269 residues), 322.3 bits, see alignment E=1.2e-100 PF00448: SRP54" amino acids 106 to 305 (200 residues), 241.9 bits, see alignment E=9.1e-76

Best Hits

Swiss-Prot: 42% identical to FTSY_BUCAP: Signal recognition particle receptor FtsY (ftsY) from Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)

KEGG orthology group: K03110, fused signal recognition particle receptor (inferred from 95% identity to sch:Sphch_1644)

Predicted SEED Role

"Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1)" in subsystem Bacterial Cell Division or Two cell division clusters relating to chromosome partitioning or Universal GTPases (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (312 amino acids)

>GFF318 Signal recognition particle receptor FtsY (Sphingobium sp. HT1-2)
MTDTGTSWRDRLFGGLKRTSDKLGENLTGLFTKAALDDQTLDEIEEALIMSDLGPAMAGR
VRDRLAEGRYNKELTEEYLREIIAEEIEKVLAPVARPLEIEAFPRPQVILVIGVNGSGKT
TTIAKLANNFLEQDYGVMLAAGDTFRAAAIGQLKVWAERLGVPIVAGKEGGDAAGIVFDA
VKQATATGIDVLIVDTAGRLQNKTELMDELAKVRRVLGRLNPAAPHDVVLVLDATTGQNA
LNQIEVFKETAQVTGLVMTKLDGTARGGVLVAAAEKYRLPIHAIGVGEKIEDLRPFDAGD
MARAIAGTAYAR