Protein Info for GFF3141 in Sphingobium sp. HT1-2

Annotation: Protein translocase subunit SecY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 27 to 46 (20 residues), see Phobius details amino acids 80 to 102 (23 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 154 to 174 (21 residues), see Phobius details amino acids 186 to 203 (18 residues), see Phobius details amino acids 215 to 236 (22 residues), see Phobius details amino acids 272 to 293 (22 residues), see Phobius details amino acids 322 to 343 (22 residues), see Phobius details amino acids 374 to 396 (23 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 24 to 433 (410 residues), 418.1 bits, see alignment E=1.9e-129 PF00344: SecY" amino acids 80 to 422 (343 residues), 370.4 bits, see alignment E=4e-115

Best Hits

Swiss-Prot: 49% identical to SECY_RICTY: Protein translocase subunit SecY (secY) from Rickettsia typhi (strain ATCC VR-144 / Wilmington)

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 88% identity to sjp:SJA_C1-06470)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>GFF3141 Protein translocase subunit SecY (Sphingobium sp. HT1-2)
MASRADQLASNLSLAKFSQATDLKKRLWFTLGALIVFRFLSFVPLPGIDPTALAAWSQKS
AGGILDIFNTFSGGALSRASLITLGIMPYITASIVVQLAASLSPQLAAIKKEGESGRKKL
NQYTRYGTVGLTAVQGYAAAANWQAQGVVVDPGMLFVVSAIISLIGGTMFLLWLGEQITS
RGIGNGTSLIIMAGIVAQLPVTLSNLFKSGSEGSISGLVIFLVVVLGFGLIAFICFMERA
QRRVLIQYPKRQTRQGLMQADRSHLPLKVNTAGVIPPIFASSLLLLPLTISQFMGVKADD
DSRWSSIVLTINQYLSHGSPFYMGLYGLGIVFFCFFYTAVVFNPEETADNLKRNGGFIPG
IRPGKNTENYLDYVLTRITVIGAAYLAFICLVPEFAIARAGIPFYLGGTSLLIVVNVTVD
TVTQIQSHLLAHQYGDLIKKAKLKGRLR