Protein Info for GFF3128 in Xanthobacter sp. DMC5

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 transmembrane" amino acids 41 to 62 (22 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details PF00672: HAMP" amino acids 206 to 258 (53 residues), 47.2 bits, see alignment 4.4e-16 PF00512: HisKA" amino acids 266 to 329 (64 residues), 34.7 bits, see alignment E=3e-12 PF02518: HATPase_c" amino acids 375 to 484 (110 residues), 87.8 bits, see alignment E=1.4e-28

Best Hits

KEGG orthology group: None (inferred from 86% identity to xau:Xaut_3518)

Predicted SEED Role

"Sensor protein basS/pmrB (EC 2.7.3.-)" in subsystem Lipid A modifications or Orphan regulatory proteins (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (485 amino acids)

>GFF3128 Adaptive-response sensory-kinase SasA (Xanthobacter sp. DMC5)
VKGEGAPAGAGPLGNGGRGYGAIASPIAHAARLVRTTAFKLLAAYLVVFALFAVSVIVYT
AWHTRALIQGQVADDLDREVVGLSDQYRIGGIQRLVYVIDRRTRRPGSSIYVLSNFQGEV
LAANVTDLPIGLLDKEGTRFTTYNRPDDPVAKSHVAFVQTMFLPGGYRLLVGRDIEERDT
LRDLVARPAQWAVVLIVVLGLAGGVFVTRRVLKRIDSMTATAETIMAGNLSGRLALAGTE
DEFDRLAHSLNAMLDRIEGLMVGLKEVSDNIAHDLKTPLTRLRNRAEEALRTGRTEDDWR
AALETTIEESAGLIRTFDALLMIARAEAGQGRATMGDVDLAEIAEAVSELYEPLADEQGL
DLTVSATPTTVHGVKELLAQALSNLIDNAIKYGRPADGGRGRITVTLKREGTDAVLTVAD
TGPGIPPADRERVVERFVRLEASRTRPGSGLGLSLVGAIARLHGGTLGFSDNGPGLVATF
RLPTK