Protein Info for PS417_15995 in Pseudomonas simiae WCS417

Annotation: peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 490 PF00413: Peptidase_M10" amino acids 106 to 214 (109 residues), 24 bits, see alignment E=4.8e-09 PF08548: Peptidase_M10_C" amino acids 270 to 489 (220 residues), 227 bits, see alignment E=2.8e-71 PF00353: HemolysinCabind" amino acids 353 to 378 (26 residues), 18.5 bits, see alignment (E = 2.4e-07) amino acids 364 to 397 (34 residues), 38.4 bits, see alignment (E = 1.4e-13)

Best Hits

KEGG orthology group: K01406, serralysin [EC: 3.4.24.40] (inferred from 47% identity to pfl:PFL_3210)

Predicted SEED Role

No annotation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U2U0 at UniProt or InterPro

Protein Sequence (490 amino acids)

>PS417_15995 peptidase (Pseudomonas simiae WCS417)
MCPRSQDQASLPDESAFMTAITSRASTTFQTIEQFQHRDDRGGGIQHNGLPSKTPEEATA
RLWRGSAGWPDKNGDGRYDVTYTFREPPEDKHQRQHNKSGFTHVLENQRQQTRRSLQSIA
DVANVRFTEGPKTASSEGHITLGNYADLYNKKGQSVAAYPQTSLPNPKDRFSGDAWFVDT
KDDQSVPNASHGDAGRFTLVHELGHALGLSHPSQYDVSSGSAKAGYLEDSESHTTMSYLG
ERHGYMNHGGIRASAPQLDDISAYQQEYGANPETRKDDTTYGFNSNTDRDFLSVKADQDK
MVAAIWDGGGTDTLDFSGYQQDQQISLKAGTFSDVGGLKGNVSIAYGVTIENAVGGFGND
LLVGNDAANTLNGGEGNDRIYGAGGADILWGGKGNDVFVYGKTNESTRDAPDQIMDFVSG
EDRVDVSGIRATQGDKPLTFVRAFSGASGEAMVTYDPAVQRSTLQISGKPDEPAFLLVVH
GKLQQSDIVS