Protein Info for PS417_15830 in Pseudomonas simiae WCS417

Annotation: GNAT family acetyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 PF13302: Acetyltransf_3" amino acids 33 to 169 (137 residues), 30.4 bits, see alignment E=5.8e-11 PF00583: Acetyltransf_1" amino acids 79 to 169 (91 residues), 36.3 bits, see alignment E=6.2e-13

Best Hits

Swiss-Prot: 60% identical to ATSE4_PSEAE: Acetyltransferase PA5475 (PA5475) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: None (inferred from 74% identity to pfo:Pfl01_3341)

Predicted SEED Role

"Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U7V4 at UniProt or InterPro

Protein Sequence (187 amino acids)

>PS417_15830 GNAT family acetyltransferase (Pseudomonas simiae WCS417)
MQTVKEHNERAVDVYAKVTGHHWIEPLKDGRHVLIRPLTDEDREREYAFIKRLSPESRHM
RFLAQINEPSKAMLDQLMDTDNDQRMAYIALTHDNGKLTEIGISRYAATGEHVCECAVTV
ADEWKHLGLGTHLMTHLIKAARRNAFTQMYSIDAASNTPMRDLARSLGFDTSSDPDNSSQ
VIHRLHL