Protein Info for PS417_15615 in Pseudomonas simiae WCS417

Annotation: short-chain dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 PF23441: SDR" amino acids 6 to 204 (199 residues), 33.3 bits, see alignment E=6.7e-12 PF00106: adh_short" amino acids 6 to 203 (198 residues), 125.8 bits, see alignment E=3.2e-40 PF08659: KR" amino acids 7 to 186 (180 residues), 40.2 bits, see alignment E=7.3e-14 PF13561: adh_short_C2" amino acids 14 to 216 (203 residues), 102.8 bits, see alignment E=4.6e-33

Best Hits

KEGG orthology group: None (inferred from 89% identity to pfs:PFLU3609)

Predicted SEED Role

"Oxidoreductase, short chain dehydrogenase/reductase family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UJ06 at UniProt or InterPro

Protein Sequence (285 amino acids)

>PS417_15615 short-chain dehydrogenase (Pseudomonas simiae WCS417)
MEFTGKTALVTGGARGLGLSYARALAQGGARVVISDIGADNAGVGSDASVVQAAADTLQA
EGLNVIGHGGDLSTNTGCQQLIAYAIEAFGQLDILIHNAGWVGYQNIADLDAAFLQRAMD
INLYAPLWLCKHAWPHLLRSSAPRIILTTSDRAMYTQYEQTGLVAYSAGKMAQLGIMNAL
SHEGAEAGIKVNAISPVAKTRMWGVTEEPDELKPDWVTPGVVFLASEQCQDSGYILRASN
GQFTATRFTENPGVDYPRNLARIKASSAEAVAAAWNSIKQAQPLS