Protein Info for GFF3050 in Sphingobium sp. HT1-2

Annotation: Prolipoprotein diacylglyceryl transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 transmembrane" amino acids 32 to 50 (19 residues), see Phobius details amino acids 70 to 88 (19 residues), see Phobius details amino acids 108 to 125 (18 residues), see Phobius details amino acids 137 to 155 (19 residues), see Phobius details amino acids 186 to 205 (20 residues), see Phobius details amino acids 214 to 231 (18 residues), see Phobius details amino acids 251 to 269 (19 residues), see Phobius details TIGR00544: prolipoprotein diacylglyceryl transferase" amino acids 21 to 275 (255 residues), 236.9 bits, see alignment E=1.5e-74 PF01790: LGT" amino acids 22 to 269 (248 residues), 255.7 bits, see alignment E=1.9e-80

Best Hits

Swiss-Prot: 68% identical to LGT_SPHWW: Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase (lgt) from Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

KEGG orthology group: K13292, phosphatidylglycerol:prolipoprotein diacylglycerol transferase [EC: 2.-.-.-] (inferred from 93% identity to sch:Sphch_0314)

Predicted SEED Role

"Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-)" (EC 2.4.99.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.-.-.-

Use Curated BLAST to search for 2.-.-.- or 2.4.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (288 amino acids)

>GFF3050 Prolipoprotein diacylglyceryl transferase (Sphingobium sp. HT1-2)
LILDLVAAASSAIRFDQLGLSPVALDLGFFTLKWYSLAYLAGILIGYWYLLKLIAQPGSP
MARRHADDMIFYATLGIIIGGRLAYVFFYQPEILQHPLDIFKLWNGGMSFHGGAAGVSLG
ILYMARKEKLSWLRIHDYVACVVPFGLFFGRLANFVNGELWGKETDVPWAMIFPTGGPFA
RHPSQLYEAFFEGIILFCILAFAFWKTKARYKPGMLVGLFVFFYGVFRFGVEYFREADAQ
LMEFAARTGLHMGQWLCVPMILGGLYLIVTAKGRRVRVEPIAGSASVS