Protein Info for GFF3044 in Sphingobium sp. HT1-2

Annotation: Outer membrane protein W precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 223 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13505: OMP_b-brl" amino acids 16 to 223 (208 residues), 49.6 bits, see alignment E=5.3e-17 PF03922: OmpW" amino acids 27 to 223 (197 residues), 188 bits, see alignment E=1.8e-59

Best Hits

KEGG orthology group: K07275, outer membrane protein (inferred from 77% identity to sjp:SJA_C2-00650)

Predicted SEED Role

"Outer membrane protein W precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (223 amino acids)

>GFF3044 Outer membrane protein W precursor (Sphingobium sp. HT1-2)
MHLKKMMIVAAMGAMGTALAAAPAQAKQGDVLVRVRGIMVAPTEKSGSILPGFPGEKVSV
NNGIAPEVDVTYMATDHIGFELIAATTKHSASGRSGTTGGIGKLASTWVLPPTLTMQYHP
IVEGHVRPYIGAGVNYTLFYNEDASGGLEDAVGKTKVHMSDSFGWAGQVGVDIDLNDKIF
LNLDVKYIDIDTKVRLTTAAAGTQNVKVSLDPFVFGVGVGMRF