Protein Info for GFF3041 in Xanthobacter sp. DMC5

Annotation: L-fuculose phosphate aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00596: Aldolase_II
  • amino acids 8 to 187 (180 residues), 151.8 bits, E=1e-48

Best Hits

Swiss-Prot: 49% identical to OTNC_HAEIN: 3-oxo-tetronate 4-phosphate decarboxylase (otnC) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 86% identity to rhi:NGR_b20300)

MetaCyc: 49% identical to 3-dehydro-4-phosphotetronate decarboxylase (Haemophilus influenzae Rd KW20)
RXN-18589 [EC: 1.1.1.409, 4.1.1.104]; RXN-18588 [EC: 1.1.1.409, 4.1.1.104, 1.1.1.408]

Predicted SEED Role

"Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases"

MetaCyc Pathways

• L-threonate degradation (2/4 steps found)
• D-erythronate degradation I (1/3 steps found)
• D-threonate degradation (1/3 steps found)
• D-erythronate degradation II (1/4 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.408 or 1.1.1.409 or 4.1.1.104

Protein Sequence (238 amino acids)

>GFF3041 L-fuculose phosphate aldolase (Xanthobacter sp. DMC5)
MDETRLREEICRFGRSLFERGLTPGSSGNISLRLDDGGWLVTPTNASLGFLDPPRISRLD
AAGRLLSGDPPTKEIPLHSALYETRGTARAIVHLHSTNSVALTMLPEIDPRAALPAMTPY
YLMRAGQTALLPYYRPGDPAVADAIRGLAGRYTSVLLANHGPVVAGDTLEAAVFATEELE
ETAKLYLLLRGLNPRYLSPGQVDDLVKTFGLTLPAPDAHHDHDHAHHTHDGHAYPRKD