Protein Info for GFF3029 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details PF07715: Plug" amino acids 70 to 172 (103 residues), 65.1 bits, see alignment E=3.9e-22

Best Hits

Predicted SEED Role

"Outer membrane vitamin B12 receptor BtuB" in subsystem Coenzyme B12 biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (681 amino acids)

>GFF3029 hypothetical protein (Sphingobium sp. HT1-2)
VPLVKVAPARRTRRRMGEYMKSITVSRAALALSLAIASPAFADEGEGDSIVVTGTSLEET
LPQQLSRYGHAIEIVTDTQIRDAAAIDTARALEAVPGLFIRSQSGPFSYVDIALQGSRTK
DVLWTMDGIRLNNRLYGGTSPNDTMAASMIERIEVLKGGESLFYGTQAAAGVINVVTRDF
SDDLGGQINASLDSFAGTSLDGYVRGAIGQHRFVVWANRSQSDGYRPYDVMQPSATDRAR
GYDLWSAGIKYQYDIAPDLRLNALYQHTKADLDNISATRTKQSRNDRNEEVASLRLDYTG
EDGVQFFLKGYFHDWKTAYVQIRNPIPAGPPQVIYPAGTFWGYQDYGGSAVVQLNMLRGI
DTLIGYDFQSFNGRDDVLLIAPTDEQVHAGIFQLRTNDELSSKGRIAAGLRYNKAKGSEK
TIWNVSGRYDVSDALFVEANGGTSFVLPDASQLYGNDPCCEVGNPNLKPEESLNLNAALG
GALAGGAIRWKATYFNRRIIDLLDTTYDDPAFPDGTYINVRDKVRARGAELELNADLSGG
WGLSASYTYSRVRNQGSSVQRDRNPEQYGRAAIVYAPQTGCFGANLSANWVGDVWSTASG
FGRMNYGNYAVVDAGAHLWLDQARRNRFGVNVENLFDKDYASTGYRSAVSDAGVLDGSNS
RFLYFYRGVPRTLRVSYGLSF