Protein Info for GFF3019 in Sphingobium sp. HT1-2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF07969: Amidohydro_3" amino acids 77 to 552 (476 residues), 348.4 bits, see alignment E=1.1e-107 PF01979: Amidohydro_1" amino acids 346 to 551 (206 residues), 40 bits, see alignment E=3.1e-14

Best Hits

Predicted SEED Role

"Exoenzymes regulatory protein AepA in lipid-linked oligosaccharide synthesis cluster"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (560 amino acids)

>GFF3019 hypothetical protein (Sphingobium sp. HT1-2)
MFSRREMLARGATGLAGLALSSSLWARTQMLDTAYVNATVWTGEGMPTARSAIGIAGGRI
AAIGAAAVKAQSGKTTRIIDLGGAFVMPGFTDAHTHFLTGSYLLSQPNLREAKSPQEFAR
IVGEAAKSLKPGQWLQGGSWDAELWGGELPDRSWMDPVTPNTPVAVQRLDLHMLALNSLA
LKLAGIDRNTPDVAGGMIVRDKDGNPTGILKDAAMDLVKRAIPAPTDADKEDAARQGIAH
GLSKGVVQVHTTELDWITHDTLRRLRAKGETDMRFYSFVPLQDWAKLKALIDAEGRGDDW
VRWGGLKLQYDGSLGSRTAMFYRPYDDAPDNEGFPIHKRADVQQWTNDADAAGLQITIHG
IGDKANDEALDIFAAAAAKNGRRDRRFRIEHAQHLTQAAIPRFAQQQVIASVQPYHAIDD
GRWAIQRVGAERLKGTYAFKSLLDAGAKVAFGSDWPVAPLDPLTGVAAAVLRQTIDGANP
GGWLPEQKISMLQALHAYTATNAFAGFSDDRMGLLKPGMLADFAVLDANLFAIDPAKIGA
TKVLRTIVGGRQRFGEGSDI