Protein Info for GFF3011 in Sphingobium sp. HT1-2

Annotation: Di-tripeptide/cation symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 71 to 93 (23 residues), see Phobius details amino acids 104 to 124 (21 residues), see Phobius details amino acids 130 to 151 (22 residues), see Phobius details amino acids 163 to 182 (20 residues), see Phobius details amino acids 188 to 209 (22 residues), see Phobius details amino acids 233 to 252 (20 residues), see Phobius details amino acids 281 to 304 (24 residues), see Phobius details amino acids 317 to 338 (22 residues), see Phobius details amino acids 348 to 371 (24 residues), see Phobius details amino acids 383 to 406 (24 residues), see Phobius details amino acids 412 to 433 (22 residues), see Phobius details TIGR00924: amino acid/peptide transporter (Peptide:H+ symporter)" amino acids 4 to 222 (219 residues), 202.3 bits, see alignment E=7.7e-64 PF07690: MFS_1" amino acids 71 to 397 (327 residues), 76.7 bits, see alignment E=1.7e-25 PF00854: PTR2" amino acids 102 to 213 (112 residues), 94.3 bits, see alignment E=8e-31 amino acids 231 to 409 (179 residues), 35.5 bits, see alignment E=5.6e-13

Best Hits

KEGG orthology group: K03305, proton-dependent oligopeptide transporter, POT family (inferred from 53% identity to pzu:PHZ_c1809)

Predicted SEED Role

"Di-/tripeptide transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>GFF3011 Di-tripeptide/cation symporter (Sphingobium sp. HT1-2)
MNQGDRAFLGHPRGLAYLLFTEAWERFSYYGMQSLLALYLVKHLLQPGQADGLLFFDAFR
QLYGGLDGQPLASAIVGTYFASVYVTPILGGLVADRLLGRHRTVLLGALTMMAGHFLMAV
QAAFLPALGLLVLGSGLFKGNLASQIGALYGRDDPRRDGAFQLYYLGINIGLIAAPLVIG
TLAETRGWHVGFAVAGVGMGIATIIYLAGRRHLPVDDYRPRSKGRGRMTGQDLRGLLGIV
LLIPLLAITLLPNNQIFNAYLIWGDAHLELTLGGLRVPTSWLITLDAGLGLTILAALPFV
YRLYARHRPEPGDLAKLTIGSLFATGGMLCLALGSALAGPDGRTGLGWAIAFHLLNGIGF
AHILPVSLALFTRAAPPRQAGLAIGLYYLVFFLGNILVGWVGGFYARMPATAFWLLHAGI
AAGCGAIFLILTLRKAIFRSD