Protein Info for GFF3001 in Xanthobacter sp. DMC5

Annotation: putative MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 34 to 54 (21 residues), see Phobius details amino acids 67 to 89 (23 residues), see Phobius details amino acids 98 to 122 (25 residues), see Phobius details amino acids 129 to 151 (23 residues), see Phobius details amino acids 163 to 182 (20 residues), see Phobius details amino acids 188 to 207 (20 residues), see Phobius details amino acids 241 to 259 (19 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details amino acids 309 to 326 (18 residues), see Phobius details amino acids 332 to 356 (25 residues), see Phobius details amino acids 370 to 392 (23 residues), see Phobius details amino acids 398 to 417 (20 residues), see Phobius details PF12832: MFS_1_like" amino acids 36 to 400 (365 residues), 56.3 bits, see alignment E=2.9e-19 PF07690: MFS_1" amino acids 45 to 319 (275 residues), 92.9 bits, see alignment E=2e-30 amino acids 278 to 427 (150 residues), 45.8 bits, see alignment E=4.3e-16

Best Hits

Swiss-Prot: 53% identical to Y2456_MYCTU: Uncharacterized MFS-type transporter Rv2456c (Rv2456c) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 80% identity to xau:Xaut_1628)

Predicted SEED Role

"MFS transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>GFF3001 putative MFS-type transporter (Xanthobacter sp. DMC5)
MVAGEVQGVGQGGVAADVPTQGPSRRAMLGLDALNFFLADVRDGLGPYLAIYLLAVRGPE
QGWTEATVGFVMTIAGLTGLLAQTPAGALIDSSRNKPAFVIAGALAVTVACLSLPFLSNF
YLVAGSQSLAAMAGAIFPPALSGITLGLVGPKAFARRIGRNEAFNHLGNAVSAAIAAGTA
VLFGPIVVFWLMAVLAALSIGAMLVVPRREIDDTLARGLAHDAAHHEHPSGLKTLLSSRP
LLIFALTCFLFHLSNAAMLPTTGQLLTYVVGKEQATSLIALCIVAAQCVMVSMAIMVGAK
ADAWGRKPIFLVAFAVLALRGALYTLSNDPFWLFAVQCLDGVGAGIFGALFPVVVADLTR
GTGRFNVSQGAVATAQGLGAAFSASIAGVTIVAAGYSAAFLTLSAIAAAGFLLYLFAMPE
TGAAAAEAPAQPPAGSAAVSP