Protein Info for GFF2996 in Sphingobium sp. HT1-2

Annotation: Homolog of fucose/glucose/galactose permeases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 transmembrane" amino acids 23 to 42 (20 residues), see Phobius details amino acids 61 to 79 (19 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 117 to 141 (25 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 202 to 224 (23 residues), see Phobius details amino acids 249 to 272 (24 residues), see Phobius details amino acids 288 to 307 (20 residues), see Phobius details amino acids 317 to 336 (20 residues), see Phobius details amino acids 342 to 364 (23 residues), see Phobius details amino acids 376 to 394 (19 residues), see Phobius details amino acids 400 to 420 (21 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 387 (358 residues), 83.6 bits, see alignment E=1.4e-27 PF00083: Sugar_tr" amino acids 53 to 175 (123 residues), 28.5 bits, see alignment E=7.8e-11 TIGR01272: glucose/galactose transporter WARNING" amino acids 108 to 417 (310 residues), 296.9 bits, see alignment E=1.1e-92

Best Hits

KEGG orthology group: K02429, MFS transporter, FHS family, L-fucose permease (inferred from 90% identity to sjp:SJA_C1-09620)

Predicted SEED Role

"Predicted mannose transporter, GGP family" in subsystem Mannose Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>GFF2996 Homolog of fucose/glucose/galactose permeases (Sphingobium sp. HT1-2)
MAGPISSGAAPVATHNPGTRYGPALALLASLFFMWGFITVINNTLLPHLRSVFELSYTQT
TLIESVWFIAYFVASIPSAKLIERVGYQKSLVIGLLIMAAGALGMTVAASIPSYGVTLVM
LFVIASGITLLQVAANPYVAVVGKPETASSRLNLVQAMNSAGTMLAPMFGAYLILGRSKA
GTAQGEVVLTQAERLADAQSVILPYVLVAIVLVVLAFVIARFPLPAMGSATSRLAKEERK
KHSLWSHRNLVFGIPAIFIYLIAEIGVANLFVNFVSQPTIANLTHEQAGNYLSLLWGGMM
VGRFAGSAIMQKFDAGHVLAAFSVGAFIVMMVTVFTTGPVAMWSLILVGLFHSIMFPTIF
TLGIKGLGPLTEEGSGLLVMAIAGGALVVVQGWMADHYGLQTSFLLTAACELYVLFYALW
GSKTTQALPEPELH