Protein Info for GFF2985 in Sphingobium sp. HT1-2

Annotation: Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 196 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details TIGR00681: K+-transporting ATPase, C subunit" amino acids 8 to 188 (181 residues), 208.8 bits, see alignment E=3.6e-66 PF02669: KdpC" amino acids 9 to 188 (180 residues), 240 bits, see alignment E=8e-76

Best Hits

Swiss-Prot: 61% identical to KDPC_RHILO: Potassium-transporting ATPase KdpC subunit (kdpC) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)

KEGG orthology group: K01548, K+-transporting ATPase ATPase C chain [EC: 3.6.3.12] (inferred from 63% identity to sch:Sphch_1026)

Predicted SEED Role

"Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (196 amino acids)

>GFF2985 Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1) (Sphingobium sp. HT1-2)
MFTDFKSALRPALTMTLLFALLLGIAYPLALTGIGQAVFPSQANGSLVEDQGKVVGSTII
GQAFASDIYFHSRPSAAGKGYDGLASSGSNYGPTSQALADRVKTDVETLQAATPGRFVPS
DLVTTSASGLDPHISPEAAFYQVDRVAAAREIDAARVRSLVEQSVEQPLLGFIGEPRVNL
FDLNRRLDAIDAKRTK