Protein Info for GFF2913 in Variovorax sp. SCN45

Annotation: ABC transporter, permease protein (cluster 3, basic aa/glutamine/opines)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 transmembrane" amino acids 17 to 42 (26 residues), see Phobius details amino acids 52 to 76 (25 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 181 to 202 (22 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 12 to 108 (97 residues), 90.9 bits, see alignment E=3.1e-30 PF00528: BPD_transp_1" amino acids 37 to 213 (177 residues), 64.6 bits, see alignment E=5.3e-22

Best Hits

Swiss-Prot: 37% identical to YCKA_BACSU: Probable amino-acid ABC transporter permease protein YckA (yckA) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 81% identity to hse:Hsero_4606)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>GFF2913 ABC transporter, permease protein (cluster 3, basic aa/glutamine/opines) (Variovorax sp. SCN45)
MSLGHFTFTHLMYLVQAIGWTLVLSAIAFVLGAVGGFGLMLARISPRPWLRWFAVVYIEC
IQGIPLLILLFIVYFGLSVYGLSLPSLVAAGLAMMIYVSAYLGDIWRGCIEAMPKPQWEA
SECLALSRWQTLRLVIIPQAVRLSLPPTVGFLVQIIKMTSLASVIGFVELTRAGQIINNT
IFQPFLVFFLVGAFYFALCYPLSRWSEAMEKKLNVANR