Protein Info for GFF2904 in Sphingobium sp. HT1-2

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 434 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 56 to 80 (25 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 112 to 130 (19 residues), see Phobius details amino acids 142 to 159 (18 residues), see Phobius details amino acids 179 to 201 (23 residues), see Phobius details amino acids 229 to 253 (25 residues), see Phobius details amino acids 265 to 285 (21 residues), see Phobius details amino acids 297 to 316 (20 residues), see Phobius details amino acids 322 to 342 (21 residues), see Phobius details amino acids 380 to 406 (27 residues), see Phobius details PF07690: MFS_1" amino acids 22 to 369 (348 residues), 88.3 bits, see alignment E=4.9e-29 PF05977: MFS_3" amino acids 52 to 405 (354 residues), 99.2 bits, see alignment E=2.1e-32

Best Hits

KEGG orthology group: None (inferred from 80% identity to sch:Sphch_3514)

Predicted SEED Role

"MFS permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (434 amino acids)

>GFF2904 Uncharacterized MFS-type transporter (Sphingobium sp. HT1-2)
MSSSAAAPHPLHFGNFRAYLVGRFCATLAQYSMMILLAWQAYNVARETMSTGEASAQLGL
IGLAQFLPLFFLTPVTGWVADHFDRRIITRLTLALLMLAAAVLAFATYEGWVSLPLIFGI
AVIVGIARAFNGPAYGALAPNLVPPAVLPTAIALSSVAWQTGDILGKAVGGYAYAIEPWA
AYALSAALFGVGLISMMMIGPVPQPPRQQGRHPIRQMIDGFTYLKSNRLVLATITLDLFA
VLLAGATALLPVYARDILHVGSTGYGHLAIAPGIGAALTALWFSFRPMKTQVGLKMLAAV
ILFGLATIAFGCTAFLPRDIAVEAGIAALIVLGGADMVSVFVRQSLVQLHTPDAMRGRVS
SLSQLTISASNELGEAESGFLAALVGPIAAVIGGGVGAILVTIFWARLFPELRLARTFDP
PDLREADISQETAQ