Protein Info for GFF2887 in Sphingobium sp. HT1-2

Annotation: TldE/PmbA family protein, Actinobacterial subgroup

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 transmembrane" amino acids 225 to 246 (22 residues), see Phobius details PF01523: PmbA_TldD_1st" amino acids 36 to 89 (54 residues), 29.4 bits, see alignment 1.1e-10 PF19290: PmbA_TldD_2nd" amino acids 144 to 195 (52 residues), 25.8 bits, see alignment 1.8e-09 PF19289: PmbA_TldD_3rd" amino acids 222 to 438 (217 residues), 147.3 bits, see alignment E=6e-47

Best Hits

KEGG orthology group: None (inferred from 74% identity to xcb:XC_0094)

Predicted SEED Role

"TldE/PmbA family protein, Actinobacterial subgroup" in subsystem Putative TldE-TldD proteolytic complex

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (444 amino acids)

>GFF2887 TldE/PmbA family protein, Actinobacterial subgroup (Sphingobium sp. HT1-2)
MSILTEAQAKAILTKVVALSKADECTAQLTGKIQGNIRFARNDVSTAGLTDDIELAVQVA
YGKKVGTATINQFDDASLERVVRRAETLANLAPDNPEFMPAVDRQAYKASPTFAQSTADI
TPEYRAQVASNSITACKSQKLIAAGYLEDNQSFVAIANSKGNFGYQRSTMLDYTCTVRTE
DGRGSGWVGTDTQDATRFKADSDIQIAMRKASASSEAKALEPGKYTVILEPMAAAGLIGF
MFYFFGAREADEGRSFLSKKGGGNKLGEQVFGPQVNFYTDPWDPVAPCLPWDDDGLARQR
VDMVKDGKVTNLNYSRYWASKQGKPAIGQMGNILMTGGTKTTADLVRSTERGVLVTRTWY
IRMVDPQTVLLTGLTRDGTFYVENGQIKYPIKNFRFNESPVIMLNNVEELGRPVRVPPDE
VSMNIVVPPMKLRDFTFTSLSDAV