Protein Info for PS417_14755 in Pseudomonas simiae WCS417

Annotation: UV damage repair endonuclease UvdE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF03851: UvdE" amino acids 42 to 267 (226 residues), 146.5 bits, see alignment E=5e-47

Best Hits

KEGG orthology group: None (inferred from 93% identity to pfs:PFLU3430)

Predicted SEED Role

"UV damage repair endonuclease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U272 at UniProt or InterPro

Protein Sequence (343 amino acids)

>PS417_14755 UV damage repair endonuclease UvdE (Pseudomonas simiae WCS417)
MTHPRIGFACQYRHPERLLSASALKLIEGPFNPRTTTLRWMDSVTPQVARDKLVEVVTHN
LAAQLRLLAYVAELPPTLRMLRLSSDLLPFYSHPKVAAVYTDPAIERQLEEGFAAIGELA
RASDIRLSFHPGQYCVLGSENPGVVENSLAEFEYHADMIRMMGYGRRFQDLKCNVHIAGR
LGVEGTRAVWARLSEVARNCITFENDEKTYGLDHCLQVADLAPVVLDIHHCWINENEYID
PHSERVARVIESWRGVRPTMHYSQPQEVLQALGFDAEHKLEMDALLKVVAKRDLYAHSAQ
MWNRWTNDYALQFFDRFDIMLESKDKNVAAWGFYEHFKRRSVQ