Protein Info for GFF2880 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: Urea ABC transporter, urea binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 PF13458: Peripla_BP_6" amino acids 60 to 397 (338 residues), 266.4 bits, see alignment E=5.5e-83 TIGR03407: urea ABC transporter, urea binding protein" amino acids 61 to 420 (360 residues), 502.7 bits, see alignment E=2.6e-155 PF13433: Peripla_BP_5" amino acids 62 to 422 (361 residues), 406 bits, see alignment E=1.6e-125

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 91% identity to del:DelCs14_0221)

Predicted SEED Role

"Urea ABC transporter, urea binding protein" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>GFF2880 Urea ABC transporter, urea binding protein (Hydrogenophaga sp. GW460-11-11-14-LB1)
MKHLSDPNAQSPETPETPEASRRRVLQMLGVAGLAGLPAWSFGQPTASVNTTKLAVTDTE
VTVGQLHSSTGTMAISETGSIQAEQLAIDEINAMGGILGRKIKVIKEDGASDWPTFAEKS
KKLLINDRCAAVFGCWTSASRKAVLPVFEKENGLLYYPTFYEGLEQSKNVIYTGQEATQQ
ILYSLDWAQKEKKAKTFFLIGSDYIWPRTSMKIARKHIENFQKGKVVGEEYYPLGSTNFG
SLMNKIKLQKPDCIFCAVVGGSNVAFYKALKAAGITGDKQLLVTLSVTEDEMTGVGGENF
AGFYSSMKYFQTLDNANNKKFVAAFKAKYGKDAVIGDVTQAGYLGPWLWKAAVEKAKSFD
VDKVVAASRTGIELTTAPEGYVKLDPNHHLWSKSRIAMGMPDATFKVVAESPELIKPDPF
PKGYQ