Protein Info for GFF2867 in Xanthobacter sp. DMC5

Annotation: 4-hydroxybenzoate transporter PcaK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 transmembrane" amino acids 38 to 59 (22 residues), see Phobius details amino acids 72 to 92 (21 residues), see Phobius details amino acids 102 to 121 (20 residues), see Phobius details amino acids 127 to 148 (22 residues), see Phobius details amino acids 160 to 182 (23 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details amino acids 273 to 293 (21 residues), see Phobius details amino acids 309 to 330 (22 residues), see Phobius details amino acids 338 to 358 (21 residues), see Phobius details amino acids 364 to 385 (22 residues), see Phobius details amino acids 397 to 421 (25 residues), see Phobius details amino acids 427 to 448 (22 residues), see Phobius details PF07690: MFS_1" amino acids 42 to 320 (279 residues), 119.1 bits, see alignment E=2.1e-38 amino acids 313 to 446 (134 residues), 44.5 bits, see alignment E=1e-15 PF00083: Sugar_tr" amino acids 70 to 459 (390 residues), 175.1 bits, see alignment E=2.5e-55

Best Hits

KEGG orthology group: K08369, MFS transporter, putative metabolite:H+ symporter (inferred from 44% identity to bpu:BPUM_0293)

Predicted SEED Role

"Transporter, MFS superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (460 amino acids)

>GFF2867 4-hydroxybenzoate transporter PcaK (Xanthobacter sp. DMC5)
MKNISMGKADSAHAEVIRDVAARIERLPFSRWHLKARILIGTATFFDAFDALTIAQVLPV
LRPLWKLSGPQVGFLISTGYLGQLVGALVAGMCAERFGRLPTMIGAICIMSVMSLACAFA
SDYETLLVFRTIQGLGLGAQVPIAAVYISEIAKAHKRGRFFILYECVFTFGLFASGLIGS
FVVPHLGWQAMFFIGVLPIIIGVSLGFLLPESPRWLASRNRVADAQAAMARIESEIEAST
GQKLAPPTEWVPADPRRSSWRDLVGPDYIRRTVVVWVIWFSTFLITYGLGTWLPTLYRSV
FNLPLDTALRFGTIGSLMQLAGGLTAGFVIDRIGRRRLFMIALFGAAAALLSIWFVGLTS
VPQFVVLSGIAYYFAGLSVLGIYLYTPEIYPTRARAIGTALGTAWLRLASMVGPLIVGFF
VADGIGMVFLVFAAAAIIAGIVVSALAIETTNRSLEDISR