Protein Info for GFF2866 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 387 transmembrane" amino acids 37 to 60 (24 residues), see Phobius details amino acids 72 to 92 (21 residues), see Phobius details amino acids 98 to 117 (20 residues), see Phobius details amino acids 130 to 153 (24 residues), see Phobius details amino acids 164 to 184 (21 residues), see Phobius details amino acids 217 to 236 (20 residues), see Phobius details amino acids 243 to 266 (24 residues), see Phobius details amino acids 278 to 294 (17 residues), see Phobius details amino acids 300 to 322 (23 residues), see Phobius details amino acids 337 to 355 (19 residues), see Phobius details amino acids 360 to 382 (23 residues), see Phobius details PF07690: MFS_1" amino acids 14 to 215 (202 residues), 73.7 bits, see alignment E=1.3e-24 amino acids 216 to 379 (164 residues), 70.2 bits, see alignment E=1.6e-23 PF12832: MFS_1_like" amino acids 33 to 348 (316 residues), 34.7 bits, see alignment E=1.1e-12

Best Hits

KEGG orthology group: None (inferred from 91% identity to vpe:Varpa_1949)

Predicted SEED Role

"putative inner membrane efflux protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (387 amino acids)

>GFF2866 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
VKGSELLRVIGAQVCLHATMAGMRLATPLLALQQGYSAAAVGVLISLFALTQVFLALPAG
RFADRHGFKRPLWLSVIAAVVGAGLVVVFPVFPVMCLSALLTGGATGATVIALQRHVGRS
AHDPTQLKRVFSWLAIAPAAANFVGPFLAGMLIDHAGRAPADMLAFRVCFAVMAALPLVC
WLLARGADEPPLAPPLAGATPTRAWDLLREPMFRRLLFVNWLQSSSWDVHAFVLPVLGHD
RGISASVIGSILGAFAVAAAVIRVVLPVIASRASERSVILSSTIVTALVFAVYPLLEAAW
AMGVCSVILGFALGAVQPMVMSMLHQITPHTRHGEALGLRLMTINASSVAMPMLFGSLGA
LIGIAGVFWVVGGVLALGARATWGLKV