Protein Info for GFF2863 in Xanthobacter sp. DMC5

Annotation: HTH-type transcriptional regulator BenM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 transmembrane" amino acids 91 to 108 (18 residues), see Phobius details PF00126: HTH_1" amino acids 3 to 62 (60 residues), 87.5 bits, see alignment E=4.5e-29 PF03466: LysR_substrate" amino acids 91 to 291 (201 residues), 130.7 bits, see alignment E=5.1e-42

Best Hits

Swiss-Prot: 73% identical to CATR_ACILW: Probable cat1 operon transcriptional activator from Acinetobacter lwoffii

KEGG orthology group: None (inferred from 76% identity to pde:Pden_1173)

Predicted SEED Role

"Aromatic hydrocarbon utilization transcriptional regulator CatR (LysR family)" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (313 amino acids)

>GFF2863 HTH-type transcriptional regulator BenM (Xanthobacter sp. DMC5)
MDLRQLRYFVGVARERNFTRAAQQLNIAQPPLSRQIQALEDELGVALLIRNSRPVRLTEA
GRLFYEQALQVLGRVDQMRAATRRVGLNQNSVLSIGFVASTLYGGLPSLVRKLRHRAPDI
EIQVLEMMSIQQIPALKEGRIDIGFGRLHHSDSGVVEIVLREERLTVAIPRDTPLAQDSA
PLPIGALTGQKLIVYPKEPRPGYADQVLNLLHGHDVRPAEVHEVREIQTALGLVAAETGL
CVIPSSARQMRSDVHYRLLEGERATSPVILYHRVGDTSPYIDLVKEVIKEMYAENPSWLS
AEHNLPTRPSFAE