Protein Info for PS417_14575 in Pseudomonas simiae WCS417

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 transmembrane" amino acids 18 to 40 (23 residues), see Phobius details amino acids 57 to 79 (23 residues), see Phobius details amino acids 90 to 113 (24 residues), see Phobius details amino acids 119 to 143 (25 residues), see Phobius details amino acids 154 to 177 (24 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details amino acids 241 to 265 (25 residues), see Phobius details amino acids 277 to 300 (24 residues), see Phobius details amino acids 308 to 327 (20 residues), see Phobius details amino acids 333 to 358 (26 residues), see Phobius details amino acids 372 to 395 (24 residues), see Phobius details amino acids 401 to 421 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 19 to 234 (216 residues), 93.6 bits, see alignment E=2e-30 amino acids 250 to 432 (183 residues), 39.7 bits, see alignment E=4.6e-14 PF07690: MFS_1" amino acids 23 to 381 (359 residues), 104.6 bits, see alignment E=8.3e-34 amino acids 276 to 429 (154 residues), 40.1 bits, see alignment E=3.3e-14

Best Hits

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 97% identity to pfs:PFLU3383)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U772 at UniProt or InterPro

Protein Sequence (445 amino acids)

>PS417_14575 MFS transporter (Pseudomonas simiae WCS417)
MTSPSTEQVSPQTLRKVIIAAGIGNFVEWFDFAVYGFLATTIAQQFFPSGDASAALLKTF
AVFAVAFAFRPLGGIFFGMLGDRIGRKRTLAMTILLMAGATTLIGLLPTYAAIGVAAPIL
LSLIRCAQGFSAGGEYAGACAYLMEHAPSDKRAWYGSFVPVSTFSAFAAAAVVAYALEAS
LSAEAMGSWGWRLPFLIAAPLGLVGLYLRWKLDETPAFQAVKEEHTVAHSPLKETLRNHG
AAISCLGAFVSLTALSFYMFTTYFATYLQVAGGLSRAMALLVSLIALIFAAAICPLAGLY
SDRVGRRATVMTACVLLMVVVYPSFLMASSGSFAASIVGVMLLAVGAVLCGVVTAALLSE
TFPTRTRYTASAITYNLAYTIFGGTAPLMATWLISTTGSNLSPAFYLIAVALLALAGGLA
LPETSRISLHDVGAEDKSSAPVLSR