Protein Info for GFF2844 in Sphingobium sp. HT1-2

Annotation: Cation-transporting ATPase, E1-E2 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 889 transmembrane" amino acids 57 to 79 (23 residues), see Phobius details amino acids 85 to 101 (17 residues), see Phobius details amino acids 248 to 269 (22 residues), see Phobius details amino acids 276 to 301 (26 residues), see Phobius details amino acids 687 to 708 (22 residues), see Phobius details amino acids 714 to 734 (21 residues), see Phobius details amino acids 755 to 777 (23 residues), see Phobius details amino acids 789 to 809 (21 residues), see Phobius details amino acids 821 to 842 (22 residues), see Phobius details amino acids 854 to 873 (20 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 9 to 76 (68 residues), 62.5 bits, see alignment 7.1e-21 TIGR01494: HAD ATPase, P-type, family IC" amino acids 87 to 349 (263 residues), 139.1 bits, see alignment E=7.7e-45 amino acids 592 to 712 (121 residues), 110.1 bits, see alignment E=4.7e-36 PF00122: E1-E2_ATPase" amino acids 116 to 308 (193 residues), 158.6 bits, see alignment E=3.9e-50 PF13246: Cation_ATPase" amino acids 389 to 470 (82 residues), 65.3 bits, see alignment E=1.2e-21 PF00702: Hydrolase" amino acids 512 to 636 (125 residues), 56 bits, see alignment E=2.2e-18 PF00689: Cation_ATPase_C" amino acids 707 to 878 (172 residues), 142.8 bits, see alignment E=3e-45

Best Hits

KEGG orthology group: None (inferred from 63% identity to rpb:RPB_1268)

Predicted SEED Role

"Ca ion P-type ATPase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (889 amino acids)

>GFF2844 Cation-transporting ATPase, E1-E2 family (Sphingobium sp. HT1-2)
MSSAPPVAWHALPPEEALATLSVEATGLDQRDAEARLRRYGPNALPEAPRQHPLLRFLAH
FNSVLIYFLLGAALIALLLNHGIDAAVILAVVLVNAVVGFIQEGKAEEALGAIQDMIAPH
AMVLRSGERRVVAVPDLVPGDIVLLEAGDRVPADIRLLRARGLLIDEAALTGESVAAEKH
QTLIAADAGIADQSNMAFSGTLVAAGQATGLVVETGIHTQIGRISGMLKAVEVGKTPLVR
QIDDFARLMTWSVLAGAVVLFLFAVLARGFHWIDALIAIVALSVGVVPEGLPAVITITLA
IGVQRMAARQAVIRRLPAVETLGATSVICTDKTGTLTRNEMTVRHLLLPGGDLHVSGSGY
APTGAISVAGGDDAEGLADAAPILRCGLLCNDALLRQADDGWTVQGDPMEGALVALAMKA
GLSADHVRDEWPRIDEIPFDAAYRFMATLHRAPDGSSAIFIKGAPEALLAMTGADAVAWD
ARLSAAAERGERLLGFAVKRITEAPDRIGFDDLKNGVELLGLMGFIDPPRDEARQAIAQC
RSAGIAVKMITGDHVGTAIAIARQLALDDDPQAMSGAEVEALDDAALAARVRDVDVFARS
SPEHKLRIVRALQSHGLVVAMTGDGVNDAPSLKQADVGTAMGIKGTEAAKEAAEMVLLDD
NFASIVAAVREGRTVYDNIRKVISWTLPTNGGETLAVVIAIIAGFALPMTATQILWINLV
LTVTLGLVLAFEPTEPGTMERRPRAAGAPLLSPFLLWRIMLVSVLMGAMALGIFFYAQHV
GHDIDTARTMVVNMLIVGEIFYLFNVRFLHMRSLTLRGAMGTPIVLAAIVAVVIAQLLFT
YAPFMHEIFDSRPLSLTDGLMIIGLGGAMFALLELEKLAAHRLAWFEDI