Protein Info for GFF2840 in Sphingobium sp. HT1-2

Annotation: Ribosome-associated ATPase RbbA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 916 transmembrane" amino acids 566 to 586 (21 residues), see Phobius details amino acids 721 to 744 (24 residues), see Phobius details amino acids 771 to 794 (24 residues), see Phobius details amino acids 800 to 822 (23 residues), see Phobius details amino acids 829 to 849 (21 residues), see Phobius details amino acids 891 to 911 (21 residues), see Phobius details PF00005: ABC_tran" amino acids 31 to 179 (149 residues), 93.8 bits, see alignment E=3.7e-30 amino acids 296 to 439 (144 residues), 104.1 bits, see alignment E=2.5e-33 PF12698: ABC2_membrane_3" amino acids 572 to 908 (337 residues), 149.1 bits, see alignment E=4.5e-47 PF12679: ABC2_membrane_2" amino acids 673 to 850 (178 residues), 47.2 bits, see alignment E=4.7e-16 PF01061: ABC2_membrane" amino acids 724 to 880 (157 residues), 60.7 bits, see alignment E=3.9e-20

Best Hits

Swiss-Prot: 65% identical to RBBA_ECOLI: Ribosome-associated ATPase (rbbA) from Escherichia coli (strain K12)

KEGG orthology group: K13926, ribosome-dependent ATPase (inferred from 64% identity to abo:ABO_1848)

Predicted SEED Role

"ABC-type multidrug transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (916 amino acids)

>GFF2840 Ribosome-associated ATPase RbbA (Sphingobium sp. HT1-2)
VNQPAPIGAPTVDPVVRLSGVRLHYGKTQALRGIDLDIPGGRMIGLIGPDGVGKSSLLSL
VAGAHVIQDGDVYVLGGDMRDKRHRSDVCPRIAYMPQGLGKNLYPTLSVEENLQFFGRLF
GHDGAERRRRIDALTRATGLDPFLARPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTG
VDPLARAQFWDLINDIRQTQAQMSVIVATAYMDEAQRFDWLVAMDDGQILDTGTPAEIFA
RTGTSSLEEAFIAVLPEEKKRGHEPVIIPPLEASEDDIAIEAQGLTMRFGDFTAVDHVSF
RIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGKAWLFGNAVDPDDMSTRKRVGYMSQA
FSLYTELTVRQNLEFHAHLFHVPREDIPARVAEMADRFDLGPVMEELPDSLPLGIRQRLS
LAVAMVHKPELLILDEPTSGVDPVARDGFWRLLAELSRRDKVTIFISTHFMNEAMRCDRM
SMMHAGHVLDSDAPARLIEKRGAPDLEQAFIGYLVDAGGDTRPPDEESALKDMAQAEHGT
IRRGFSPQRALTYAWRETLELQRDPVRATLALIGSLILMLVIGFGMTTDINELNYAVLDR
DNSILSQNYALDISGSSYFVEHAPIRDYDDLDRRMKDGELALVIEIPPGFGRDIAAGRQV
TVGAWFDGANPQRAETVQGYIQGLHQHWLSQQAAARGSAVGSSFSIENRYRYNPDVQSLP
AMVPIVIPLLLLMLPAMLTALAVVREKEIGSIINLYVTPVSRSEFLLGKQLPYVVLALVN
FLLMVLMAIFIFGVPVKGSFPTLLLAAAIYCVTATGMGLLASAVTRSQIAAMFLAMIGTM
IPATTYGGMTDPVSSMEGSARIIGDIYPASHMFTISRGVFAKALGFSDLAGSFLPLAISA
PLIVGIAIMLLKKQEA