Protein Info for PS417_14470 in Pseudomonas simiae WCS417

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF06342: DUF1057" amino acids 46 to 175 (130 residues), 24.3 bits, see alignment E=3.2e-09 PF12146: Hydrolase_4" amino acids 66 to 269 (204 residues), 60.1 bits, see alignment E=4e-20 PF00561: Abhydrolase_1" amino acids 68 to 319 (252 residues), 88.2 bits, see alignment E=1.5e-28 PF12697: Abhydrolase_6" amino acids 68 to 322 (255 residues), 71.7 bits, see alignment E=2.9e-23

Best Hits

KEGG orthology group: None (inferred from 92% identity to pfs:PFLU3362)

Predicted SEED Role

"hydrolase, alpha/beta fold family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U754 at UniProt or InterPro

Protein Sequence (333 amino acids)

>PS417_14470 alpha/beta hydrolase (Pseudomonas simiae WCS417)
MPLTRAFCIASLLAATAAPAFAATYGPELQGFEYPYPLQHFEFQSQGTSLQMGYMDVPAK
GQANGRSVVLMHGKNFCGATWESSIRALSEAGYRVIAPDQIGFCSSSKPDHYQYSFQQLA
TNTHQLLEKLGIQKATVIGHSTGGMLATRYALMFPEQTEQLGLVNPIGLEDWKALGVPSL
TVDQWYARELKVNADGIRNYQLNTYYVGRWKPEYERWVDMYAGLSNGPGHTRVAWNSALI
YDMIFTQPVYYEFKNLQMPTLLLIGTSDNTAIGKDVAPPAVKAKLGDYAVLGKQVAQLIP
HATLVEFPGLGHAPQMEEPARFHTALLQGLNAL