Protein Info for GFF2829 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Rtn protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 transmembrane" amino acids 16 to 36 (21 residues), see Phobius details amino acids 70 to 84 (15 residues), see Phobius details amino acids 222 to 239 (18 residues), see Phobius details amino acids 246 to 264 (19 residues), see Phobius details PF12792: CSS-motif" amino acids 44 to 239 (196 residues), 160.2 bits, see alignment E=4.7e-51 PF00563: EAL" amino acids 274 to 502 (229 residues), 206.2 bits, see alignment E=4.9e-65

Best Hits

Swiss-Prot: 76% identical to PDED_ECOLI: Probable cyclic di-GMP phosphodiesterase PdeD (pdeD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to sei:SPC_1902)

Predicted SEED Role

"Rtn protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (533 amino acids)

>GFF2829 Rtn protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MQTAQRIINHYRRNRFIVCTICALVTLILTLSIRFISERNLNHHRTVAFANHAVDALDNV
LHPLLVGRNILLPLLELPCATAHLPLRKQAARLQTIRSIGLVKEGILYCSSIFGARNTPI
RQLQPDLPAVGDLLLLSTDQSLLKGSPILIQWYPASADGQDGVMEIVNIDLLTTMLLEPQ
QPQITSASLTVGKRHLLYGRGVVDTLPELKKDEERYQLSSRHFPFTISVSGPSAGVLAFK
HLPTQLPLAVLLSLLIGYIAWLATASRMSFSWEINLALAEREFELFCQPLLNARTQQCTG
VEILLRWNNPRQGWISPDVFIPIAEEHNLIAPLTRYVIAETIRQRHYFPINHQFHIGINV
AASHFRHGVLLKDLNQYWFSAEPVQQLVLELTERDALLDVDYRLMRELHRKGVKLAIDDF
GTGNSSLSWLEKLRPDILKIDKSFTAAIGTDAVNSTVTDIIIALGQRLNIELVAEGVENQ
TQAQHLRQHGVQMLQGYLYAKPMPISEFPQWLAGSAPPPARHNGQIMSAMPHL