Protein Info for GFF2827 in Sphingobium sp. HT1-2

Annotation: Aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 558 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF04389: Peptidase_M28" amino acids 307 to 514 (208 residues), 153.2 bits, see alignment E=3.7e-49

Best Hits

KEGG orthology group: None (inferred from 68% identity to swi:Swit_0029)

Predicted SEED Role

"peptidase, M20/M25/M40 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (558 amino acids)

>GFF2827 Aminopeptidase (Sphingobium sp. HT1-2)
MTMSPLSRASRAAWRTLACAGLLSASALAVAATTAPQFDVARIVKDIKILASDEFEGRGP
ATRAETKTIDYIAKQMAAAGLKPAGDKGTWFQDVPLRMSNITGTPSLSMTVGGAAQPLTQ
GTEIAVRAAETGQSAVKFANLPLVFVGYGVKAPERGWDDFKGVDLKGKIMVVLVNDPDFE
GGEGDFGGKLMTYYGRWTYKYEEAARQGAAGVLVVHESEPASYGWATVKNSNTNTMFDIV
RADPKSAHTQMEGWIQKDLAAKLLAASGVDFEAAKAAARKKDFKPIPLKATMSADYAVKS
EIITSHNVASILPGSKYPDETVIYSAHWDHLGIGAPDAKGDTIYNGARDNASGTAALLEL
ARAYAKGPKPERSVLFLAVTAEEKGLLGSEYYADNPLRPLATTAGVINMDGPFAAEKTVN
FSISGAAKLDLLTLLTQEGEKLGRHYTPDARPEAGSFYRSDHFPMAKRGVPAISFNPGRE
LVNGGAARGKELGDIYTRDRYHQPADQYDDSWNTSSWEGDMTLLYNVGRRVADGHDWPNW
SNDSEFRAARDASQAQRK