Protein Info for GFF2818 in Sphingobium sp. HT1-2

Annotation: TonB-dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 559 TIGR01782: TonB-dependent receptor" amino acids 9 to 558 (550 residues), 433.7 bits, see alignment E=8e-134 PF00593: TonB_dep_Rec_b-barrel" amino acids 84 to 526 (443 residues), 154 bits, see alignment E=6.2e-49

Best Hits

Predicted SEED Role

"N-acetylglucosamine-regulated TonB-dependent outer membrane receptor" in subsystem Chitin and N-acetylglucosamine utilization or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (559 amino acids)

>GFF2818 TonB-dependent receptor (Sphingobium sp. HT1-2)
MATFIDVPVGNNTSAQTRHSTTTDYSLNLKWKPVDNLTITADGQYVDAKTKNLRSIFGLN
GVADTLYQDISGSVPVVNIGSETRLTNPATYTSAFYLDNLNESKASDKTARLDAEYRFDA
GILSSIKAGFRYADRKNRTIDTGYRYTGLSGIPSELETVDLGDFFRGDADLFGNIIAFNR
GIIRNYQNTLDTLGIASAPAYTQSGTNQQRQKTFTGYATAFFKADPIDGNIGVRVVRTNL
DVSGYYQQTPIVLDENGNEVSGPTVFNPIAVSQDYTSVLPSLNLRVHLTDNLQLRFAAAK
NISRPTFTQLNPSLTISEPGAAQQDQIHTASGGNPYLKPMKSDNLDATVEWYFSRTGSLT
AAAFYKNIKNYIQTAVSYRDVTFDNGNSYEYEVTSYNNVAKGKVKGFELAYQQFFDFLPG
PFDGLGMQANFTYVDSQAPSPATSGPVTNVPLELLSKYNYNIVGIYEKGGLSARVAYNWR
SKYVVTTAGNGTGSLPVFNKPFGQLDASISYNVTPQFALALDGTNLTNTRRATYFGIDSR
PRDVVVNDRRISLTARITY