Protein Info for PS417_14355 in Pseudomonas simiae WCS417

Annotation: sugar dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01370: Epimerase" amino acids 10 to 200 (191 residues), 24.4 bits, see alignment E=3.6e-09 PF00106: adh_short" amino acids 10 to 202 (193 residues), 164.1 bits, see alignment E=5.6e-52 PF08659: KR" amino acids 10 to 173 (164 residues), 31.4 bits, see alignment E=3.7e-11 PF13561: adh_short_C2" amino acids 17 to 252 (236 residues), 191.4 bits, see alignment E=3.9e-60

Best Hits

Swiss-Prot: 56% identical to YGFF_ECOLI: Uncharacterized oxidoreductase YgfF (ygfF) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU3332)

Predicted SEED Role

"short chain dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U729 at UniProt or InterPro

Protein Sequence (253 amino acids)

>PS417_14355 sugar dehydrogenase (Pseudomonas simiae WCS417)
MATGSSAPLILITGGSRGVGAATARLAAAQGYDVAISYINNEAAALGVVADVQALGRRAL
AIRADSADPEQVAHLFRAIDETFGRIDVLVNNAAIIALQSRFEDLDVARMQRIFAINAIG
PMLCAQQAVKRMSFRHSGNGGSVINVSSGAARLGSPNEYVDYAASKGALETFTIGLSKEV
AREGIRVNCVRPGHIYTEMHASGGEPGRVDRVKDSIPMGRGGEPEEVARAVLWLAGAEAS
FITGTFLDVTGGK