Protein Info for PS417_14300 in Pseudomonas simiae WCS417

Annotation: aspartate:proton symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 45 to 65 (21 residues), see Phobius details amino acids 86 to 109 (24 residues), see Phobius details amino acids 131 to 149 (19 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details amino acids 201 to 222 (22 residues), see Phobius details amino acids 234 to 255 (22 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details amino acids 342 to 358 (17 residues), see Phobius details amino acids 364 to 386 (23 residues), see Phobius details amino acids 399 to 419 (21 residues), see Phobius details amino acids 425 to 446 (22 residues), see Phobius details amino acids 462 to 485 (24 residues), see Phobius details amino acids 491 to 512 (22 residues), see Phobius details PF13520: AA_permease_2" amino acids 11 to 455 (445 residues), 160.1 bits, see alignment E=8.8e-51 PF00324: AA_permease" amino acids 16 to 389 (374 residues), 91.5 bits, see alignment E=5.3e-30

Best Hits

Swiss-Prot: 59% identical to ASPP_BACSU: Aspartate-proton symporter (yveA) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 96% identity to pfs:PFLU3323)

Predicted SEED Role

"Aspartate-proton symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U720 at UniProt or InterPro

Protein Sequence (539 amino acids)

>PS417_14300 aspartate:proton symporter (Pseudomonas simiae WCS417)
MSAQGKFKKQLSLMDLTFIGLGAIFGSGWLFAASHVSAIAGPAGIISWLIGGFAVLLLGI
VYCELGAALPRAGGVVRYPVYSHGPLLGYLMGFITLIAFSSLVAIEVVASRQYAAAWFPE
LTKAGSSDPTTLGWLVQFALLCLFFVLNYRSVKTFAIANNLVSVFKFIVPLLVIGVLFTF
FKPANFQVQGFAPFGLSGIEMAVSAGGVIFAYLGLTPIISVASEVKNPQRTIPIALILSV
LLSTAIYVLLQTAFLGGVPTEMLANGWAGISKELALPYRDIALALGVGWLAYLVVADAVI
SPSGCGNIYMNATPRVVYGWAQTGTFFKIFTRIDEKSGIPRPALWLTFALSVFWTLPFPS
WEALINVVSAALILSYAVAPVTVAALRRNAPQMARPFRVKGMAVLGPLSFIIAALIVYWS
GWNTVSWLLGLQILMFVVYLLCARWVPTAHLNIKQQVRSSAWLIGFYAVTILLSKLGSFG
GIGVIGHPLDTIVVAACALGIYYWGAATGVPAHLVRLEHEADESEAVDEPHAPLTPATY