Protein Info for GFF2802 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Cell volume regulation protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 31 to 53 (23 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 89 to 115 (27 residues), see Phobius details amino acids 122 to 142 (21 residues), see Phobius details amino acids 185 to 209 (25 residues), see Phobius details amino acids 225 to 255 (31 residues), see Phobius details amino acids 273 to 290 (18 residues), see Phobius details amino acids 296 to 322 (27 residues), see Phobius details amino acids 335 to 356 (22 residues), see Phobius details amino acids 363 to 383 (21 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 20 to 388 (369 residues), 222.5 bits, see alignment E=1.2e-69 PF02080: TrkA_C" amino acids 419 to 483 (65 residues), 48.2 bits, see alignment E=1.2e-16 PF03471: CorC_HlyC" amino acids 494 to 571 (78 residues), 42 bits, see alignment E=1.2e-14

Best Hits

Swiss-Prot: 100% identical to NHAP2_SALCH: K(+)/H(+) antiporter NhaP2 (nhaP2) from Salmonella choleraesuis (strain SC-B67)

KEGG orthology group: K11105, cell volume regulation protein A (inferred from 100% identity to sek:SSPA1001)

Predicted SEED Role

"Cell volume regulation protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>GFF2802 Cell volume regulation protein A (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
LDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGIGGIPFDNYPF
AYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFHLDLI
EGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQKHE
TGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISLPSGLYPMLALSGGILIFALTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVTPSDLWPIAV
PALILSIWMIFFARPLSVFTGLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLEN
ARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKVVVPPVGWPVSRVGLDIHPDNPWEQFIYQ
LSADKWCVGAALRDLHMPNETRIAALFRNNELFHPTGSTRLQEGDVLCVIGRERDLPALG
KLFSQSPPVSLDQRFFGDFILEANAKFADVALIYGLEEGTEYRDKQQTLGEIIQQLLGAA
PVVGDQVEFGGMIWTVAEKEDNVVRKIGVRVAEDEAE