Protein Info for GFF2780 in Variovorax sp. SCN45

Annotation: Phosphoesterase, PA-phosphatase related

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 transmembrane" amino acids 30 to 51 (22 residues), see Phobius details amino acids 71 to 91 (21 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 147 to 167 (21 residues), see Phobius details amino acids 178 to 196 (19 residues), see Phobius details amino acids 202 to 223 (22 residues), see Phobius details PF14378: PAP2_3" amino acids 81 to 216 (136 residues), 31.9 bits, see alignment E=1.2e-11 PF01569: PAP2" amino acids 139 to 226 (88 residues), 38.9 bits, see alignment E=7.1e-14

Best Hits

KEGG orthology group: None (inferred from 85% identity to vpe:Varpa_2131)

Predicted SEED Role

"phosphoesterase, PA-phosphatase related"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (244 amino acids)

>GFF2780 Phosphoesterase, PA-phosphatase related (Variovorax sp. SCN45)
MHSPIPLQLAPETRTPTWTADIWLRVRRHFLLKAVGTTAFTWLFFIGYFHLLRNPSFPVT
VMPLTPLDHLIPFQPYALGAYLSLWFYVGIAPGLQLTFRELVVYGLWIGGLCITGLGLFY
FWPTQIPPLSIDVTGFPGFAMLQGVDAAGNACPSMHVAVAIFTAIRIEHVLRETRTPALW
RLLNWAWFAAIAYSTLAVKQHVVLDVAAGALLGVAFALPSLYWRPGKRFRGDSPHVGADI
IGHH