Protein Info for GFF2779 in Xanthobacter sp. DMC5

Annotation: Arsenical-resistance protein Acr3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 40 to 59 (20 residues), see Phobius details amino acids 79 to 102 (24 residues), see Phobius details amino acids 114 to 136 (23 residues), see Phobius details amino acids 148 to 171 (24 residues), see Phobius details amino acids 178 to 197 (20 residues), see Phobius details amino acids 214 to 235 (22 residues), see Phobius details amino acids 241 to 267 (27 residues), see Phobius details amino acids 280 to 302 (23 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details TIGR00832: arsenical-resistance protein" amino acids 1 to 329 (329 residues), 379.2 bits, see alignment E=9.2e-118 PF01758: SBF" amino acids 47 to 242 (196 residues), 105.9 bits, see alignment E=1.1e-34

Best Hits

KEGG orthology group: K03325, arsenite transporter, ACR3 family (inferred from 89% identity to xau:Xaut_0877)

Predicted SEED Role

"Arsenical-resistance protein ACR3" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>GFF2779 Arsenical-resistance protein Acr3 (Xanthobacter sp. DMC5)
MSLFERYLTVWVGLCIVAGVLLGHLAPSVFHAIGAVEIAQVNLPVAVLIWLMIVPMLLKI
DFAALGEVGRHWRGIGVTLFVNWAVKPFSMALLGWLFIGWLFRPLLPADQIDSYIAGLII
LAAAPCTAMVFVWSNLTKGEPHFTLSQVALNDAIMVVAFAPIVALLLGLSAITVPWGTLV
LSVVLYIVIPVIVAQLLRRRLLAHGGQAALDGLLARLGPLSLVALLATLVLLFGFQGEAI
IAQPLVIALLAVPILIQVYFNAGLAYLLNRATGEAHCVAGPSALIGASNFFELAVAAAIS
LFGFTSGAALATVVGVLIEVPVMLSVVWIVNRSKNWYERTAEVGKIQPAD