Protein Info for GFF2774 in Sphingobium sp. HT1-2

Annotation: Outer membrane receptor proteins, mostly Fe transport

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 777 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07715: Plug" amino acids 50 to 153 (104 residues), 32.2 bits, see alignment E=1.3e-11 PF00593: TonB_dep_Rec_b-barrel" amino acids 370 to 730 (361 residues), 149.9 bits, see alignment E=2.2e-47

Best Hits

KEGG orthology group: None (inferred from 76% identity to swi:Swit_0687)

Predicted SEED Role

"Outer membrane receptor proteins, mostly Fe transport" in subsystem Hemin transport system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (777 amino acids)

>GFF2774 Outer membrane receptor proteins, mostly Fe transport (Sphingobium sp. HT1-2)
MRGRGWLCAGLAGVALMPGLAQAEELEAGPAQTIIVTAPGGAIDVDDALSISSRDISLTG
TPDLLGALTRNIAGITLQDAQNNPWQPNLLYRGFVASPLQGQAQGLAVYMDGARFNQPFG
DTVQFDLIPEAAIRKLSLLDASPVYGLNALGGAILLETKDGRSDPGLEASMTGGRFGYAE
ASIAGGFTRGNFSAFGAFQYSHDDGWRDHSPSHLYNGYADLGFDTEKGGLHMKLVGAKTD
LTGNGVSPVELLAADRRAVFTWPDNSRSNYGRISLHPWVALSDTTRIEGTLYAQRLTLRT
VNGDAADIEGCEDEDDAGLLCLETVGGDDDGDEAQAVLTDANGNAIADSLGGEGYGVLNR
GRTRTDAMGALVQLIDDRALMGGTNHFAIGMSYDSSRTRFDTSTELGAMTDERSVEGLGS
IIVQPDGAIAPVGLVAHSDYWGVFVQDRLPLAPGLTAELGLRWNHARIELVDQIGTALNG
RHNFRRLNPGAELDYRVSDGLSLRVGYAETNRAPTPAELSCADENAPCSLTNFFIADPPL
KQVVAKSWEAGGSGRFAVGGWTADWLVSAYRTGNHDDIQYIASDIRGRAYFQNIGKTRRQ
GVEASVKAARGGFSAGLSYAFTDATYRSALTLSSPANPEANEDGTIDVGKGDRLPGIPRH
SATLTLDYAGTLGGQRRWSIGGDLIARSGQYLVGDEANRNAKVPGYLIANIRAGIDIIPG
VTLFGEVRNLFDRHYATFGTFTEVDEIELDEAPGASDPRAYGAGAPRRWYAGVKATF