Protein Info for GFF2772 in Sphingobium sp. HT1-2

Annotation: Methylamine dehydrogenase light chain precursor (EC 1.4.99.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02975: Me-amine-dh_L
  • amino acids 68 to 178 (111 residues), 183.2 bits, E=8.4e-59

Best Hits

Swiss-Prot: 47% identical to DHML_PARVE: Methylamine dehydrogenase light chain (mauA) from Paracoccus versutus

KEGG orthology group: K15228, methylamine dehydrogenase light chain [EC: 1.4.98.1] (inferred from 59% identity to gdj:Gdia_2337)

MetaCyc: 47% identical to methylamine dehydrogenase small subunit (Paracoccus versutus)
RXN-2841 [EC: 1.4.9.1]

Predicted SEED Role

"Methylamine dehydrogenase light chain precursor (EC 1.4.99.3)" in subsystem Respiratory dehydrogenases 1 (EC 1.4.99.3)

MetaCyc Pathways

• methylamine degradation I (1/1 steps found)
• methanol and methylamine oxidation to formaldehyde (1/2 steps found)
• superpathway of C1 compounds oxidation to CO₂ (5/12 steps found)

KEGG Metabolic Maps

• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.4.98.1, 1.4.99.3

Use Curated BLAST to search for 1.4.9.1 or 1.4.98.1 or 1.4.99.3

Protein Sequence (181 amino acids)

>GFF2772 Methylamine dehydrogenase light chain precursor (EC 1.4.99.3) (Sphingobium sp. HT1-2)
MKKFDADAMGEKLLRRLAGGTSRRSMLSRLGAALVAAPAFPLLPVSRAEAAKPDRSPEAK
TAFARTAQSKDETKCDYWRYCAIDGALCTCCGGGIHSCPAGAEPSPVSWVGTCINPDDGK
AYLIAYRDCCGKPACGQCGCDNTDRETQLYMPQLNNDVIWCFGTSSMEYHCSTAVLVGAA
S