Protein Info for GFF2748 in Xanthobacter sp. DMC5

Annotation: Metal-pseudopaline receptor CntO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 731 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF07715: Plug" amino acids 84 to 182 (99 residues), 70 bits, see alignment E=2.4e-23 TIGR01783: TonB-dependent siderophore receptor" amino acids 86 to 731 (646 residues), 343 bits, see alignment E=2e-106 PF00593: TonB_dep_Rec_b-barrel" amino acids 253 to 698 (446 residues), 217 bits, see alignment E=9.5e-68

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 67% identity to azc:AZC_0182)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (731 amino acids)

>GFF2748 Metal-pseudopaline receptor CntO (Xanthobacter sp. DMC5)
MTSPLPLGARLSLSASLFVLAQLGAGTAAAQTPPAQPAAPPAWDVAGSDTDLPTIVVNAE
RGDGVVVGYQAITTSTATLTQMPVLDIPAAINTVTQEVIQDQNATTLEQVLQNISNVTVA
NTLGGTQDAFIRRGFGDNRDGGVLTNGLRTVLPRSFNATTDRVEVLKGPASTLYGIQEPG
GIINVITKKPQETFNAYLNGSLSSFGGGYGDFDVTGPINGTGLAFRFIGEWQDQNYWRNF
GDIEQGILAPSLAWYGENTTATIAYTHREYSVPFDRGTIFDLTTGKAVPVDRRIRFDEPY
NVTNGTSDLVLAGVEHAFNDAWKLKVNYAWSQDVYADNQARVIAYDSATGILTRRADATQ
DSTQHDQNLRADLTGTVTIAGMKNELLFGANVNDYDVLRTDMIRCKNKKGFNIYHPVYGT
LPACTTVSAADSDQQANQTLYSGYAQDAIYLTDQWIVVAGGSYAWYTQTAGKGRPFNLNT
DGEGGEFMPRAGLVYKATDKLSFYANYATSFVPQISIAGEIGSLPPETGVSYEAGMKFEM
LKGLTGTVAIFNIEKENVLYNEVINGETFARTAGKVRSRGFEFDISGAVTDQINLIASYG
YTDAKIVEDPQYAGNVPANVAAHTFSLFATYDFGKVWGENSLKVGGGFHGQSEAPGSAAN
NFWLPGYVVFDAMVAYTIEKPTPWAVTPLTVQLNVKNLFDTTYYVSSIGTNNLGVAVGAP
FEAVLSARMKF